Thermo Fisher Scientific Caspase 1 Polyclonal Antibody
Caspase-1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체입니다. IHC 및 IHC(P) 실험에 적합하며, 인간 Caspase-1 합성 펩타이드를 면역원으로 제작되었습니다. 염증성 Caspase 연구 및 IL-1β, IL-18 활성화 관련 연구용으로 사용됩니다.
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Applications
Immunohistochemistry (IHC)
- Tested Dilution: -
- Publications: View 1 publication
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:25–1:50
- Publications: View publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Published species | Rat |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to the second quarter of human Caspase 1 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Storage conditions | 4°C |
| Shipping conditions | Wet ice |
| RRID | AB_779519 |
Product Specific Information
- Recommended positive control: Placenta
- Formalin-fixed paraffin-embedded tissue sections require high-temperature antigen unmasking with 10 mM citrate buffer (pH 6.0) prior to immunostaining.
Target Information
Caspases are a family of cysteine proteases divided into apoptotic and inflammatory subfamilies. Unlike apoptotic caspases, inflammatory caspases are mainly involved in immune responses to microbial pathogens. Members include caspase-1, -4, -5, and -12, which activate proinflammatory cytokines such as IL-1β and IL-18.
Caspase-1 was first identified as the IL-1β-converting enzyme and later found to be a mammalian homolog of the C. elegans cell death gene ced-3, whose overexpression can induce apoptosis in fibroblasts.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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