Thermo Fisher Scientific GNB3 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000-1:3,000

-

Immunocytochemistry (ICC/IF)

1:100-1:500

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthesized peptide derived from human GNB3(Accession P16520), corresponding to amino acid residues D290-N340. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:GNB3,uniProtId:P16520-1,ncbiNodeId:9606,antigenRange:290-340,antigenLength:340,antigenImageFileName:PA5-103881_GNB3_P16520-1_Rabbit.svg,antigenImageFileNamePDP:PA5-103881_GNB3_P16520-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice

RRID

AB_2853213

Product Specific Information

Antibody detects endogenous levels of total GNB3.

Target Information

Heterotrimeric guanine nucleotide-binding proteins in this gene is associated with essential hypertension and obesity. This polymorphism is also associated with the occurrence of the splice variant GNB3-s, which appears to have increased activity. GNB3-s is an example of alternative splicing caused by a nucleotide change outside of the splice donor and acceptor sites. Additional splice variants may exist for this gene, but they have not been fully described.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.