Thermo Fisher Scientific GNB3 Polyclonal Antibody
GNB3 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 Immunocytochemistry에 적합합니다. 인간, 마우스, 랫트 반응성을 가지며, 합성 펩타이드 항원을 이용해 제작되었습니다. 액상 형태로 -20°C에서 보관하며 연구용으로 사용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:3,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human GNB3 (Accession P16520), corresponding to amino acid residues D290–N340. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2853213 |
Product Specific Information
Antibody detects endogenous levels of total GNB3.
Target Information
Heterotrimeric guanine nucleotide-binding proteins encoded by this gene are associated with essential hypertension and obesity. This polymorphism is also linked to the occurrence of the splice variant GNB3-s, which shows increased activity. GNB3-s represents alternative splicing caused by a nucleotide change outside of the splice donor and acceptor sites. Additional splice variants may exist but have not been fully described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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