Thermo Fisher Scientific MEK5 Recombinant Rabbit Monoclonal Antibody (ARC0711)
Recombinant rabbit monoclonal antibody against MEK5 for WB and ELISA applications. Reactive with human, mouse, and rat. High purity (affinity chromatography) and stable liquid form for research use only.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
ELISA
- Tested Concentration: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | ARC0711 |
| Immunogen | Synthetic peptide within amino acids 250–350 of human MEK5 (Q13163) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol, 0.05% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2849077 |
Product Specific Information
Immunogen sequence:
DVYRKMPEHV LGRIAVAVVK GLTYLWSLKI LHRDVKPSNM LVNTRGQVKL CDFGVSTQLV NSIAKTYVGT NAYMAPERIS GEQYGIHSDV WSLGISFMEL A
Target Information
MAP2K5 (MEK5) is a serine/threonine kinase belonging to the MAP kinase family. It specifically interacts with and activates MAPK7/ERK5. MAP2K5 can be phosphorylated and activated by MAP3K3/MEKK3 and atypical protein kinase C isoforms (aPKCs).
This signaling cascade is involved in growth factor–stimulated cell proliferation and muscle cell differentiation.
The rs3743354 polymorphism in the MAP2K5 promoter may influence colorectal cancer risk.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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