Thermo Fisher Scientific MEK5 Recombinant Rabbit Monoclonal Antibody (ARC0711)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

ARC0711

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 250-350 of human MEK5 (Q13163) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:MEK5,uniProtId:Q13163-1,ncbiNodeId:9606,antigenRange:250-350,antigenLength:448,antigenImageFileName:MA5-35172_MEK5_Q13163-1_Rabbit.svg,antigenImageFileNamePDP:MA5-35172_MEK5_Q13163-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.5 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol, 0.05% BSA

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2849077

Product Specific Information

Immunogen sequence: DVYRKMPEHV LGRIAVAVVK GLTYLWSLKI LHRDVKPSNM LVNTRGQVKL CDFGVSTQLV NSIAKTYVGT NAYMAPERIS GEQYGIHSDV WSLGISFMEL A

Target Information

MAP2K5 (MEK5) serine/threonine kinase (mitogen-activated protein kinase 5) or MEK5 is a dual specificity protein kinase that belongs to the MAP kinase family which specifically interacts with and activates MAPK7/ERK5. MAP2K5 itself can be phosphorylated and activated by MAP3K3/MEKK3, as well as by atypical protein kinase C isoforms (aPKCs). The signal cascade mediated by MAP2K5 is involved in growth factor stimulated cell proliferation and muscle cell differentiation. The rs3743354 polymorphism in the MAP2K5 promoter may affect the risk of developing colorectal cancer (CRC).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.