Thermo Fisher Scientific TOP1 Recombinant Rabbit Monoclonal Antibody (ARC0708)
TOP1 단백질을 인식하는 재조합 토끼 단클론 항체로, Western blot, IHC, ICC, ELISA, IP 등 다양한 응용에 적합합니다. 인간 및 마우스 시료에 반응하며, 고순도의 Affinity Chromatography 정제 제품입니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:6,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:800 |
| Immunocytochemistry (ICC/IF) | 1:100–1,000 |
| ELISA | 1 µg/mL |
| Immunoprecipitation (IP) | 0.5–4 µg antibody for 200–400 µg extracts |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | ARC0708 |
| Immunogen | Synthetic peptide corresponding to amino acids 1–100 of human DNA topoisomerase I (TOP1) (P11387) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.33 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol, 0.05% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | –20°C, avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2849074 |
Product Specific Information
Immunogen sequence:
MSGDHLHNDS QIEADFRLND SHKHKDKHKD REHRHKEHKK EKDREKSKHS NSEHKDSEKK HKEKEKTKHK DGSSEKHKDK HKDRDKEKRK EEKVRASGDA
Target Information
This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. It catalyzes transient breaking and rejoining of a single DNA strand, allowing strands to pass through one another and altering DNA topology. The gene is localized to chromosome 20 and has pseudogenes on chromosomes 1 and 22.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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