Thermo Fisher Scientific GCK Polyclonal Antibody
GCK 단백질을 인식하는 Rabbit Polyclonal Antibody로 Western blot에 적합. Human, Mouse, Rat 등 다양한 종에 반응. 항원 친화 크로마토그래피로 정제된 액상형 제품. 보존제 무첨가, -20°C 보관.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific GCK Polyclonal Antibody
Applications
- Western Blot (WB)
Tested Dilution: 1:1,000
Publications: [References not provided]
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues surrounding Ser380 of human GCK |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol |
| Contains | No preservative |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11008031 |
Product Specific Information
- It is not recommended to aliquot this antibody.
- This antibody is not cross-reactive with HPK or other members of the GCK family.
Target Information
Hexokinases phosphorylate glucose to produce glucose-6-phosphate, thus committing glucose to the glycolytic pathway.
Alternative splicing of this gene results in three tissue-specific forms of glucokinase, one found in pancreatic islet beta cells and two found in liver.
The protein localizes to the outer membrane of mitochondria.
Unlike other forms of hexokinase, this enzyme is not inhibited by its product glucose-6-phosphate but remains active while glucose is abundant.
Mutations in this gene have been associated with non-insulin dependent diabetes mellitus (NIDDM), maturity onset diabetes of the young, type 2 (MODY2), and persistent hyperinsulinemic hypoglycemia of infancy (PHHI).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(PA5-17711_GCK_P35557-1_Rabbit.svg 및 PA5-17711_GCK_P35557-1_Rabbit_PDP.jpeg)
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.