
Thermo Fisher Scientific Phospho-EGFR/ErbB2 (Tyr1173, Tyr1248) Polyclonal Antibody
EGFR/ErbB2 단백질의 인산화 부위를 인식하는 토끼 폴리클로날 항체. Western blot에 적합하며, 항원 친화 크로마토그래피로 정제됨. 인체 시료 반응성. 보존제 무첨가, -20°C 보관.
- 카탈로그번호
- PA517844
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic phosphopeptide corresponding to residues surrounding pTyr1248 of human ErbB2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Antigen affinity chromatography |
| Storage buffer | 0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol |
| Contains | No preservative |
| Storage conditions | -20°C |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11001612 |
Product Specific Information
It is not recommended to aliquot this antibody.
Target Information
The protein encoded by this gene is a transmembrane glycoprotein and a member of the protein kinase superfamily. It serves as a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor, leading to receptor dimerization, tyrosine autophosphorylation, and subsequent cell proliferation. Mutations in this gene are associated with lung cancer. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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