Thermo Fisher Scientific WIPI1 Recombinant Rabbit Monoclonal Antibody (ARC1652)
WIPI1 단백질을 인식하는 재조합 토끼 단클론 항체로, Western blot과 ELISA에 적합합니다. HEK293 세포에서 발현되었으며, 인간·마우스·랫트에 반응합니다. 고순도 친화 크로마토그래피 정제, 안정한 PBS/glycerol buffer에 보관됩니다. 연구용 전용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | ARC1652 |
| Immunogen | Synthetic peptide corresponding to amino acids 1–100 of human WIPI1 (UniProt ID: Q5MNZ9) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.6 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS (pH 7.3) with 50% glycerol, 0.05% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2849717 |
Product Specific Information
Immunogen sequence:
MEAEAADAPP GGVESALSCF SFNQDCTSLA TGTKAGYKLF SLSSVEQLDQ VHGSNEIPDV YIVERLFSSS LVVVVSHTKP RQMNVYHFKK GTEICNYSYS
Target Information
WIPI1 (WD repeat domain, phosphoinositide interacting-1) is involved in autophagy and may regulate protein trafficking in recycling pathways. It contains three WD repeats forming a 7-bladed propeller structure that facilitates protein–protein interactions. WIPI1 localizes to cytoplasmic vesicles, endosomes, clathrin-coated vesicles, and the trans-Golgi network. It is expressed in multiple tissues, with highest levels in heart, testis, placenta, pancreas, and skeletal muscle. Upregulation of WIPI1 has been observed in various tumors, suggesting a potential role in carcinogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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