Thermo Fisher Scientific TADA2L Monoclonal Antibody (S1)

Applications

Western Blot (WB)

• Tested Dilution: 1:500–1:1,000

ELISA

• Tested Dilution: 1:500–1:1,000

Product Specifications

Product Specific Information

Protein sequence:
MDRLGSFSND PSDKPPCRGC SSYLMEPYIK CAECGPPPFF LCLQCFTRGF EYKKHRSDHT YEIMTSDFPV LDPSWTAQEE MALLEAVMDC GFGNWQDVAN QMCTKTKEEC EKHYMKYFIN NPLFASTLLN LKQAEEAKTA DTAIPFHSTD DPPRPTFDSL LSRDMAGYMP ARADFIEEFD NYAEWDLRDI DFVEDDSDIL HALKMAVVDI YHSRLKERQR RKKIIRDHGL INLRKFQLME RRYPKEVQDL YETMRRFARI VGPVEHDKFI ESHACRWFLS LEQYLCVYIY INRRDNGVFY VKFYK

Target Information

TADA2L (transcriptional adapter 2-like), also known as TADA2A (transcriptional adapter 2-alpha) or ADA2-like protein, is a 443 amino acid nuclear protein existing as two alternatively spliced isoforms. It is most abundantly expressed in testis but present in all tissues. TADA2L contains one SANT domain and one SWIRM domain, and interacts with GCN5 and GR (NR3C1). Its ability to bind double-stranded DNA allows it to play a role in chromatin remodeling. TADA2L is a component of both the PCAF and ATAC complexes, which have histone acetyltransferase activity on histones H3 and H4. The TADA2L gene spans 71,408 bases and maps to human chromosome 17q12. Chromosome 7 houses over 1,000 genes, comprises nearly 5% of the human genome, and has been linked to osteogenesis imperfecta, Pendred syndrome, lissencephaly, citrullinemia, and Shwachman-Diamond syndrome.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.