Thermo Fisher Scientific FMR1/FMRP Polyclonal Antibody
FMR1/FMRP 단백질을 인식하는 Rabbit Polyclonal Antibody로 Western blot 및 Immunoprecipitation에 적합합니다. 인간 FMRP의 582–632번 잔기 영역을 면역원으로 사용하였으며, 액상 형태로 1 mg/mL 농도입니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- A305200Ax (2개 옵션)
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific FMR1/FMRP Polyclonal Antibody
Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 2–10 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 582–632 of human FMRP (UniProt ID: Q06787-1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Orangutan
Target Information
FMR1 binds RNA and is associated with polysomes. The protein may be involved in mRNA trafficking from the nucleus to the cytoplasm.
A trinucleotide repeat in the 5′ UTR is normally found at 6–53 copies, but an expansion to 55–230 repeats is the cause of fragile X syndrome.
Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure.
Multiple alternatively spliced transcript variants encoding different protein isoforms and located in different cellular locations have been described for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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