Thermo Fisher Scientific Cadherin 17/LI Cadherin (Liver-Intestine Marker) Recombinant Rabbit Monoclonal Antibody (CDH17/8515R)

Applications

Immunohistochemistry (Paraffin) (IHC (P))

• Tested Dilution: Assay-dependent

Immunohistochemistry (PFA fixed) (IHC (PFA))

• Tested Dilution: 1–2 µg/mL

Product Specifications

Target Information

The CDH17 gene belongs to the cadherin superfamily, encoding calcium-dependent, membrane-associated glycoproteins. The protein consists of an extracellular region with seven cadherin domains and a transmembrane region but lacks the conserved cytoplasmic domain. It is expressed in the gastrointestinal tract and pancreatic ducts and functions as an intestinal proton-dependent peptide transporter, involved in the absorption of peptide-based drugs. CDH17 may also contribute to the morphological organization of the liver and intestine. Multiple transcript variants result from alternative splicing.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.