Thermo Fisher Scientific Cathepsin V Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 105-334 of human CTSV (NP_0013242) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Cathepsin V,uniProtId:O60911-1,ncbiNodeId:9606,antigenRange:105-334,antigenLength:334,antigenImageFileName:PA5-117101_Cathepsin_V_O60911-1_Rabbit.svg,antigenImageFileNamePDP:PA5-117101_Cathepsin_V_O60911-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

2.46 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2901731

Product Specific Information

Positive Samples: HeLa, A-549, Mouse liver, Rat liver

Immunogen sequence: VFREPLFLDL PKSVDWRKKG YVTPVKNQKQ CGSCWAFSAT GALEGQMFRK TGKLVSLSEQ NLVDCSRPQG NQGCNGGFMA RAFQYVKENG GLDSEESYPY VAVDEICKYR PENSVANDTG FTVVAPGKEK ALMKAVATVG PISVAMDAGH SSFQFYKSGI YFEPDCSSKN LDHGVLVVGY GFEGANSNNS KYWLVKNSWG PEWGSNGYVK IAKDKNNHCG IATAASYPNV

Target Information

Cathepsin V (CTSU, CTSV, CATL2, cathepsin U, cathepsin L2) is a lysosomal cysteine proteinase that influences corneal physiology, and mediates degradation of invariant chain in human thymus. Cathepsin V is present in corneal epithelium, activated macrophages, and colorectal and breast carcinomas. A 1.8-kb mRNA to Cathepsin V is present in normal human thymus and testis. Cathepsin V is a member of the peptidase C1 family. Cysteine proteinases are synthesized as preproenzymes, which are processed to the corresponding proenzymes. The proenzymes are either targeted to the lysosome or continue along the cellular secretory route.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.