Thermo Fisher Scientific NY-BR-1 Polyclonal Antibody
Thermo Fisher의 NY-BR-1 Polyclonal Antibody는 인간 NY-BR-1 단백질을 인식하는 토끼 IgG 항체로, WB, IHC(P), ICC/IF에 적합합니다. 고순도 친화 크로마토그래피 정제, 액상 형태로 제공되며 -20°C 보관이 권장됩니다. 연구용으로만 사용 가능합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human ANKRD30A (Accession Q9BXX3), corresponding to amino acid residues H1102–L1152 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2815886 |
Product Specific Information
Antibody detects endogenous levels of total AN30A.
Target Information
NY-BR-1 is a novel differentiation marker predominantly expressed in normal breast and breast cancer. It has been shown by immunohistochemistry (IHC) that NY-BR-1 is present solely in ductal epithelium of normal breast tissue. Invasive carcinoma of the breast and carcinoma in situ were positive for NY-BR-1, whereas most other tumors and normal tissues are negative, except for one-third of sweat gland carcinomas and around two percent of prostate carcinoma. NY-BR-1 is reported to express more frequently in estrogen-positive and lymph node-negative primary carcinomas, and more commonly in grade 1 than in grade 2 or grade 3. In a study by Varga et al. (2006), forty-nine percent of lymph node metastases were shown to be positive.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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