
Thermo Fisher Scientific PD-L1 Monoclonal Antibody (3D10)
인간 PD-L1을 인식하는 Mouse IgG1 단클론 항체로, IHC(P) 및 유세포분석에 적합. 0.5 mg/mL 농도의 액상 제품으로 Protein A 정제. 암 면역 회피 연구 및 PD-1/PD-L1 경로 분석에 활용 가능.
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Applications
Immunohistochemistry (Paraffin) [IHC (P)]
- Tested Dilution: 2–10 µg/mL
Flow Cytometry (Flow)
- Tested Dilution: 0.5–5 µg/10⁶ cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3D10 |
| Immunogen | Recombinant protein of human PD-L1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS with proprietary stabilizer |
| Contains | 0.01% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Positive control: Tosil
- Cellular location: Membrane
Target Information
Programmed death receptor ligand 1 (PD-L1, also known as B7-H1) is a member of the B7 family. Its receptor, programmed death receptor 1 (PD-1), negatively regulates T-cell receptor (TCR) signaling. Upon binding to PD-1, PD-L1 decreases TCR-mediated proliferation and cytokine production. PD-L1 expression is abundant in many murine and human cancers and can be upregulated by IFN-γ stimulation. Thus, PD-L1 plays a key role in tumor immune evasion.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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