Thermo Fisher Scientific Phospho-SMC1 (Ser360) Polyclonal Antibody
SMC1 단백질의 Ser360 인산화 형태를 특이적으로 인식하는 Rabbit Polyclonal 항체. Western blot에 적합하며, 인간, 마우스, 랫트 시료에서 반응. PBS/glycerol buffer에 보관되며 -20°C에서 안정적. 연구용 전용 시약.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human SMC1A (Accession Q14683), corresponding to amino acid residues around phosphorylated Ser360 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2816685 |
Product Specific Information
Antibody detects endogenous levels of SMC1 only when phosphorylated at Ser360.
Target Information
Structural Maintenance of Chromosomes (SMC) family proteins play critical roles in various nuclear events that require structural changes of chromosomes, including mitotic chromosome organization, DNA recombination and repair, and global transcriptional repression.
SMC1 and SMC3 form a heterodimeric complex required for metaphase progression in mitotic cells, responsible for sister chromatid cohesion during metaphase.
Mutations in the SMC1 gene can lead to Cornelia de Lange syndrome 2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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