Thermo Fisher Scientific Human Caspase 2 Synthetic Peptide

Thermo Fisher Scientific Human Caspase 2 Synthetic Peptide

Applications

• Control (Ctrl): Assay-dependent
• Blocking Assay (BLOCK): Assay-dependent

Product Specifications

Product Specific Information

This peptide corresponds to 16 amino acids near the amino terminus of human Caspase-2.
PEP-0225 can be used as a blocking peptide with polyclonal antibody PA5-20107.

Target Information

Caspase 2 gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis.
Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme.
The proteolytic cleavage of this protein is induced by a variety of apoptotic stimuli.
Alternative splicing of this gene results in multiple transcript variants that encode different isoforms.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.