Thermo Fisher Scientific DYNLL1 Recombinant Rabbit Monoclonal Antibody (23GB5245)
DYNLL1 단백질을 인식하는 토끼 유래 재조합 단클론 항체로, Western Blot 및 유세포 분석에 적합합니다. HEK293F 시스템에서 발현되었으며, 친화 크로마토그래피로 정제되었습니다. PBS 버퍼(50% 글리세롤 포함) 내 액상 형태로 제공되며, 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:5,000 |
| Flow Cytometry (Flow) | 1:2,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293F |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 23GB5245 |
| Immunogen | A synthesized peptide derived from human DYNLL1 (1–48 AA) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice (domestic); Dry ice (international) |
Target Information
Cytoplasmic dyneins are large enzyme complexes with a molecular mass of about 1,200 kDa. They contain two force-producing heads formed primarily from dynein heavy chains and stalks linking the heads to a basal domain containing accessory intermediate chains. The complex is involved in intracellular transport and motility.
DYNLL1 is a light chain component of this complex and also interacts with neuronal nitric oxide synthase (nNOS), inhibiting its activity by destabilizing the nNOS dimer. This regulation affects multiple biological processes through modulation of nitric oxide synthase activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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