Thermo Fisher Scientific SPHK2 Monoclonal Antibody (9C5E1)
SPHK2 단백질을 인식하는 Thermo Fisher Scientific의 Mouse Monoclonal Antibody (Clone 9C5E1)입니다. 인간 시료에 반응하며 IHC, ICC/IF, Flow Cytometry, ELISA 등 다양한 응용에 사용 가능합니다. Protein G로 정제된 액상 항체로 1 mg/mL 농도이며, 연구용으로만 사용됩니다.
- 카탈로그번호
- MA531906
- 판매단위
- pk
카탈로그
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Thermo Fisher Scientific SPHK2 Monoclonal Antibody (9C5E1)
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:200–1:1,000 |
| Flow Cytometry (Flow) | 1:200–1:400 |
| ELISA | 1:10,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 9C5E1 |
| Immunogen | Synthesized peptide of human SK2 (AA: 36–52) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term; for long-term storage, store at -20°C, avoiding freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2787529 |
Product Specific Information
MA5-31906 has been tested in indirect ELISA.
Target Information
SPHK2, along with SPHK1, catalyzes the phosphorylation of sphingosine to produce sphingosine-1-phosphate (S1P), a key signaling molecule acting through G-protein coupled receptors. S1P regulates diverse cellular processes such as motility, survival, apoptosis, migration, and cell-cell interaction. SPHK2 functions in both intra- and extracellular signaling and plays roles in cell differentiation, calcium mobilization, and apoptosis. Dysregulation of SPHKs has been linked to cancer and other pathophysiological conditions.
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
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(이미지 파일: MA5-31906_SPHK2_Q9NRA0-1_House_mouse_PDP.jpeg, MA5-31906_SPHK2_Q9NRA0-1_House_mouse.svg)
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