Thermo Fisher Scientific GCN2 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:5,000

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human

Published species

Goat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Protein corresponding to human GCN2 [aa136-aa252] if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:GCN2,uniProtId:Q9P2K8-1,ncbiNodeId:9606,antigenRange:136-252,antigenLength:1649,antigenImageFileName:720463_GCN2_Q9P2K8-1_Rabbit.svg,antigenImageFileNamePDP:720463_GCN2_Q9P2K8-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Purification

Protein G

Storage buffer

PBS, pH 7.4, with 30% glycerol, 0.1% BSA

Contains

0.09% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2762413

Product Specific Information

This antibody is predicted to react with Monkey, Pig, Bovine, Sheep.

Target Information

EIF2AK4 (GCN2) is a metabolic-stress sensing protein kinase that phosphorylates the alpha subunit of eukaryotic translation initiation factor-2 in response to low amino acid availability. It plays a role as an activator of the integrated stress response required for adapatation to amino acid starvation. Mutations in the gene lead to pulmonary vennocclusive disease 2.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.