Thermo Fisher Scientific CD97 Polyclonal Antibody
Human CD97 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB, ELISA, IP에 사용 가능. 보존제가 없는 액상 형태이며, Protein A 및 항원 친화 크로마토그래피로 정제됨. CD97 관련 면역세포 활성 및 종양 침습 연구에 적합.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1:5,000–1:10,000 |
| Immunoprecipitation (IP) | 0.2–1 µL/mg of lysate |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human CD97 protein (Met1–Gln398) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2787648 |
Product Specific Information
This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).
This antibody has specificity for Human CD97.
Target Information
CD97 is a G-protein-coupled seven-span transmembrane adhesive receptor constitutively expressed on granulocytes and monocytes, and rapidly upregulated on T and B cells upon activation.
It is produced in alternatively spliced forms, and its cellular ligand is CD55 (DAF), which protects cells from complement-mediated damage.
Interaction of CD97 on leukocytes and CD55 on vessel cells facilitates leukocyte activation and migration into tissues. CD97 also plays a role in tumor migration and invasiveness, as well as T cell regulation and peripheral granulocyte homeostasis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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