Thermo Fisher Scientific BAG5 Monoclonal Antibody (OTI1E1), TrueMAB
BAG5 단백질을 인식하는 Mouse 단일클론 항체로 Western blot에 최적화됨. Human, Mouse, Rat 반응성 보유. Lyophilized 형태로 제공되며, PBS 및 trehalose buffer 포함. 신경세포 사멸 연구 및 hsp70 상호작용 연구에 활용 가능.
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Applications
- Western Blot (WB): 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1E1 |
| Immunogen | Full-length human recombinant BAG5 protein produced in 293T cells |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
BAG5 protein is hypothesized to induce death of nigral neurons through interaction with hsp70, leading to increased protein aggregation and cell death by disinhibition of hsp70’s anti-apoptotic function.
BAG5 may play a key role in neuronal death mechanisms and act as a modulator of the hsp70/hsp40 chaperone axis. It may also coordinate localization and modulation of other BAG-containing proteins via BAG-BAG heterodimerization.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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