Thermo Fisher Scientific BAG5 Monoclonal Antibody (OTI1E1), TrueMAB

Applications

• Western Blot (WB): 1:500–1:2,000

Product Specifications

Product Specific Information

For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).

Target Information

BAG5 protein is hypothesized to induce death of nigral neurons through interaction with hsp70, leading to increased protein aggregation and cell death by disinhibition of hsp70’s anti-apoptotic function.
BAG5 may play a key role in neuronal death mechanisms and act as a modulator of the hsp70/hsp40 chaperone axis. It may also coordinate localization and modulation of other BAG-containing proteins via BAG-BAG heterodimerization.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.