Thermo Fisher Scientific Gephyrin Polyclonal Antibody
다양한 종에 반응하는 Gephyrin 단백질 검출용 Rabbit Polyclonal 항체. Western blot, IHC, ICC 등 여러 응용에 적합. 고순도 항원 친화 크로마토그래피 정제. 연구용으로 신경 관련 단백질 분석에 활용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:10,000 | View 1 publication |
| Immunohistochemistry (IHC) | – | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 | – |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:1,000 | – |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 | – |
| Immunoprecipitation (IP) | 1:100–1:500 | – |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Fruit fly |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 196–473 of Human Gephyrin |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.62 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.025% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2546512 |
Product Specific Information
- Recommended positive controls: NIH-3T3, JC, U87-MG, SK-N-SH, IMR-32, SK-N-AS, mouse brain, rat brain.
- Predicted reactivity: Mouse (100%), Rat (100%), Xenopus laevis (92%), Pig (100%), Chicken (100%), Rhesus Monkey (100%).
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Gephyrin is a neuronal assembly protein that anchors inhibitory neurotransmitter receptors to the postsynaptic cytoskeleton via high affinity binding to receptor subunit domains and tubulin dimers. In non-neuronal tissues, this protein is also required for molybdenum cofactor biosynthesis. Mutations in this gene may be associated with hyperplexia and molybdenum cofactor deficiency. Multiple alternatively spliced transcript variants exist, though not all full-length forms are known.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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