Thermo Fisher Scientific TGFBI Polyclonal Antibody
TGFBI 단백질을 인식하는 Thermo Fisher Scientific의 다클론 항체. Western blot, IHC, ICC/IF 등 다양한 응용 가능. 인간 및 랫트 반응성, 염기서열 기반 면역원 사용. 연구용으로 세포 접착 및 콜라겐 결합 연구에 적합.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.1–0.3 µg/mL | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 4–6 µg/mL | - |
| Immunocytochemistry (ICC/IF) | 10 µg/mL | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Rat |
| Published Species | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (QLYTDRTEKLRPE) corresponding to internal amino acids of TGFBI (aa 119–132) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_10985588 |
Product Specific Information
- Predicted to react with canine, mouse, and rat based on sequence homology.
- Tested in Peptide ELISA: antibody detection limit dilution 32,000.
Target Information
This gene encodes an RGD-containing protein that binds to type I, II, and IV collagens.
The RGD motif is found in many extracellular matrix proteins modulating cell adhesion and serves as a ligand recognition sequence for several integrins.
This protein plays a role in cell-collagen interactions and may be involved in endochondrial bone formation in cartilage.
It is induced by transforming growth factor-beta and acts to inhibit cell adhesion.
Mutations in this gene are associated with multiple types of corneal dystrophy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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