ELK Biotechnology Vimentin (Phospho-Tyr38) rabbit pAb
Vimentin (Phospho-Tyr38) rabbit polyclonal antibody로, 인산화된 Vimentin 단백질을 검출합니다. WB 및 ELISA에 적합하며, 세포골격 관련 연구에 활용됩니다. Human, Mouse, Rat 시료에 반응합니다. -20°C에서 1년 보관 가능합니다.
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제품명
Vimentin (Phospho-Tyr38) rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | Vimentin (Phospho-Tyr38) rabbit pAb |
| Alternative Names | VIM |
| Applications | WB; ELISA |
| Recommended Dilutions | WB: 1:500–1:10000, ELISA: 1:10000 |
| Immunogen | Synthesized phospho-peptide around the phosphorylation site of human Vimentin (Phospho-Tyr38) |
| Storage | -20°C / 1 year |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 51 kD |
| GeneID (Human) | 7431 |
| Human Swiss-Prot No | P08670 |
| Cellular Localization | Cytoplasm; Cytoplasm, cytoskeleton; Nucleus matrix; Cell membrane |
| Species Reactivity | Human: Y38; Mouse: Y38; Rat: Y38 |
Background
This gene encodes a member of the intermediate filament family. Intermediate filaments, along with microtubules and actin microfilaments, make up the cytoskeleton. The protein encoded by this gene is responsible for maintaining cell shape, integrity of the cytoplasm, and stabilizing cytoskeletal interactions. It is also involved in the immune response and controls the transport of low-density lipoprotein (LDL)-derived cholesterol from a lysosome to the site of esterification. It functions as an organizer of a number of critical proteins involved in attachment, migration, and cell signaling. Mutations in this gene cause a dominant, pulverulent cataract. [provided by RefSeq, Jun 2009]
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