
ELK Biotechnology Cleaved-Caspase-6 p11 (A194) rabbit pAb
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| Product name: | Cleaved-Caspase-6 p11 (A194) rabbit pAb |
| Alternative Names: | caspase 6, apoptosis-related cysteine peptidase |
| Applications: | WB;ELISA |
| Recommended Dilutions: | WB 1:500-2000, ELISA 1:10000-20000 |
| Immunogen: | Synthesized peptide derived from Cleaved-Caspase-6 p11 (A194) . at AA range: 150-230 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 33kD |
| GeneID(Human): | 839 |
| Human Swiss-Prot No: | P55212 |
| Cellular localization: | Cytoplasm . Nucleus . |
| Background: | This gene encodes a member of the cysteine-aspartic acid protease (caspase) family of enzymes. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic acid residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspases 7, 8 and 10, and is thought to function as a downstream enzyme in the caspase activation cascade. Alternative splicing of this gene results in multiple transcript variants that encode different isoforms. [provided by RefSeq, Oct 2015], |
| Species Reactivity: | Human;Mouse;Rat |
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