ELK Biotechnology MRP-L35 rabbit pAb
MRP-L35 단백질을 인식하는 토끼 폴리클로날 항체로, WB 및 IHC에 사용 가능. 미토콘드리아 리보솜 단백질 연구에 적합하며, 고순도 IgG 형식으로 제공. -20°C에서 1년 보관 가능.
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MRP-L35 rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | MRP-L35 rabbit pAb |
| Alternative Names | MRPL35; BM-007; 39S ribosomal protein L35, mitochondrial; L35mt; MRP-L35 |
| Applications | WB; IHC |
| Recommended Dilutions | WB 1:500–2000; IHC-p 1:50–300 |
| Immunogen | Synthesized peptide derived from MRP-L35 (AA range: 80–160) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 21 kDa |
| GeneID (Human) | 51318 |
| Human Swiss-Prot No. | Q9NZE8 |
| Cellular Localization | Mitochondrion |
| Species Reactivity | Human; Mouse |
Background
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and are involved in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit, with approximately 75% protein to rRNA composition, unlike prokaryotic ribosomes where this ratio is reversed. Prokaryotic ribosomes contain a 5S rRNA, which is absent in mammalian mitoribosomes. The proteins comprising the mitoribosome vary significantly among species in sequence and biochemical properties, making sequence homology recognition difficult. This gene encodes a 39S subunit protein, and three transcript variants have been identified. Pseudogenes corresponding to this gene are found on chromosomes 6p, 10q, and Xp (RefSeq, Jul 2008).
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