ELK Biotechnology Centriolin rabbit pAb
Centriolin 단백질을 인식하는 토끼 폴리클로날 항체로, IHC, IF, ELISA에 사용 가능. CEP110 유래 펩타이드로 면역화되어 centrosome 관련 연구에 적합. Human, Rat, Mouse 반응성. -20°C에서 1년 보관.
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다ELK Biotechnology · ELK Biotechnology Centriolin rabbit pAb
Centriolin rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | Centriolin rabbit pAb |
| Alternative Names | CCP110; CEP110; CP110; KIAA0419; Centriolar coiled-coil protein of 110 kDa; Centrosomal protein of 110 kDa; CP110; Cep110 |
| Applications | IHC; IF; ELISA |
| Recommended Dilutions | Immunohistochemistry: 1/100 - 1/300 ELISA: 1/40000 Not yet tested in other applications |
| Immunogen | The antiserum was produced against synthesized peptide derived from human CEP110 (AA range: 850-900) |
| Storage | -20°C / 1 year |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| GeneID (Human) | 9738 |
| Human Swiss-Prot No | O43303 |
| Species Reactivity | Human; Rat; Mouse |
Cellular Localization
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Recruited early and associates with growing distal tips. Recruited to the mother centriole by KIF24 (PubMed:21620453). Removed from centrioles by TTBK2, initiating ciliogenesis and localizing only to the daughter centriole in ciliated cells. In cytotoxic T lymphocytes, remains associated with the mother centriole during docking of the centrosome at the immunological synapse upon target contact (By similarity). Recruited at the distal end of the mother centriole by MPHOSPH9 (PubMed:30375385).
Background
Function: Necessary for centrosome duplication. Collaborates with CEP97 in suppressing cilia assembly. Required for correct spindle formation and regulation of cytokinesis and genome stability via cooperation with CALM1 and CETN2.
Induction: Up-regulated during the transition from G1 to S phase, peaking in S phase.
PTM: Phosphorylated by CDKs.
Subunit: Interacts with CALM1, CETN2, and CEP97.
Tissue specificity: Highly expressed in testis; intermediate levels in spleen, thymus, prostate, small intestine, colon, and peripheral blood leukocytes.
ELK Biotechnology 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.