ELK Biotechnology N-CoR rabbit pAb
N-CoR rabbit pAb는 인간 및 생쥐 시료에서 N-CoR 단백질을 검출하기 위한 폴리클로날 항체입니다. WB, IHC, IF, ELISA 등 다양한 응용에 적합하며, 고순도 IgG 형태로 제공됩니다. -20°C에서 1년 보관 가능합니다.
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제품 개요
ELK Biotechnology의 N-CoR rabbit pAb는 인간 NCoR1 유래 합성 펩타이드(AA 51–100)에 대해 생산된 폴리클로날 항체로, 핵 수용체 보조억제 단백질(Nuclear receptor corepressor 1)을 검출하는 데 사용됩니다.
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | N-CoR rabbit pAb |
| Alternative Names | NCOR1; KIAA1047; Nuclear receptor corepressor 1; N-CoR; N-CoR1 |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | WB: 1/500–1/2000 IHC: 1/100–1/300 IF: 1/200–1/1000 ELISA: 1/20000 Not yet tested in other applications |
| Immunogen | Synthesized peptide derived from human NCoR1 (AA range: 51–100) |
| Host | Rabbit |
| Storage | -20°C, 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 270 kDa |
| Gene ID (Human) | 9611 |
| Human Swiss-Prot No. | O75376 |
| Cellular Localization | Nucleus |
| Species Reactivity | Human; Mouse |
Background
This gene encodes a protein that mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex that includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p. This gene is located between the Charcot-Marie-Tooth and Smith-Magenis syndrome critical regions on chromosome 17. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 17 and 20. [RefSeq, Jun 2010]
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