ELK Biotechnology ATP5J2 rabbit pAb
ATP5J2 단백질을 인식하는 토끼 폴리클로날 항체로, IHC, IF, ELISA에 사용 가능. 인간, 생쥐, 랫트 시료에 반응. 합성 펩타이드 면역원으로 제작되었으며, -20°C에서 1년 보관 가능.
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제품명
ATP5J2 rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | ATP synthase f chain mitochondrial; ATP5JL; ATPK |
| Applications | IHC; IF; ELISA |
| Recommended Dilutions | Immunohistochemistry: 1/100 - 1/300 ELISA: 1/5000 Not yet tested in other applications |
| Immunogen | The antiserum was produced against synthesized peptide derived from human ATP5J2 (AA range: 21–70) |
| Host Species | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Gene ID (Human) | 9551 |
| Human Swiss-Prot No. | A6ND55 |
| Species Reactivity | Human; Rat; Mouse |
Background
Mitochondrial ATP synthase catalyzes ATP synthesis utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. It is composed of two linked multi-subunit complexes: the soluble catalytic core (F1) and the membrane-spanning component (Fo), which comprises the proton channel.
The catalytic portion of mitochondrial ATP synthase consists of five different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and single representatives of the gamma, delta, and epsilon subunits. The proton channel likely has nine subunits (a, b, c, d, e, f, g, F6, and 8).
ATP5J2 (ATP synthase, H+ transporting, mitochondrial Fo complex subunit F2) encodes the f subunit of the Fo complex. Alternatively spliced transcript variants encoding different isoforms have been identified for ATP5J2. ATP5J2 has multiple pseudogenes. Naturally occurring read-through transcription also exists between ATP5J2 and the downstream pentatricopeptide repeat domain 1 (PTCD1) gene.
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