ELK Biotechnology Neuralized-1 rabbit pAb

Neuralized-1 rabbit pAb

제품 개요

Neuralized-1 단백질(NEURL1)을 인식하는 토끼 폴리클로날 항체입니다. 인간, 랫, 마우스 시료에서 사용 가능하며, 다양한 응용 분야(WB, IHC, IF, ELISA)에 적합합니다.

제품 정보

세포 내 위치

Cytoplasm, perinuclear region; Cell membrane; Peripheral membrane protein; Perikaryon; Cell projection (dendrite); Cell junction (synapse, postsynaptic density).
Localized in the cell bodies of pyramidal neurons and distributed along their apical dendrites.
Colocalized with PSD95 in postsynaptic sites and with CPEB3 at apical dendrites of CA1 neurons (By similarity).
Colocalized with JAG1 at the cell surface.

Background

NEURL1B (neuralized homolog 1B), also known as neur2 or NEURL3, is a 555 amino acid protein functioning as an E3 ubiquitin-protein ligase. It contains two NHR (neuralized homology repeat) domains and one RING-type zinc finger.
NEURL4 (neuralized homolog 4), also known as neuralized-like protein 4, is a 1,562 amino acid protein expressed in various tissues. It contains six NHR domains and exists as two alternatively spliced isoforms encoded by a gene on human chromosome 17p13.1.