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ELK Biotechnology Rabaptin-5α rabbit pAb
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ELK Biotechnology Rabaptin-5α rabbit pAb

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Rabaptin-5α rabbit polyclonal antibody로, RABEP1 단백질을 인식합니다. IHC, IF, ELISA에 사용 가능하며 인간, 생쥐, 랫트 시료에 반응합니다. 세포 내 조기 엔도솜 및 재활용 엔도솜에서 Rab 단백질과 상호작용하는 단백질 연구에 적합합니다.

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ELK Biotechnology ES7966-100UL Rabaptin-5α rabbit pAb, 100UL pk판매 단위 pk ·
재고 확인 필요
402,000원VAT 포함 442,200원
ELK Biotechnology ES7966-50UL Rabaptin-5α rabbit pAb, 50UL pk판매 단위 pk ·
재고 확인 필요
301,000원VAT 포함 331,100원

ELK Biotechnology · ELK Biotechnology Rabaptin-5α rabbit pAb

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Rabaptin-5α rabbit pAb

제품 정보

항목 내용
Alternative Names RABEP1; RAB5EP; RABPT5; RABPT5A; Rab GTPase-binding effector protein 1; Rabaptin-4; Rabaptin-5; Rabaptin-5alpha; Renal carcinoma antigen NY-REN-17
Applications IHC; IF; ELISA
Recommended Dilutions Immunohistochemistry: 1/100 - 1/300
ELISA: 1/40000
Not yet tested in other applications
Immunogen The antiserum was produced against synthesized peptide derived from human RABEP1 (AA range: 549–598)
Host Rabbit
Storage -20°C / 1 year
Clonality Polyclonal
Isotype IgG
Concentration 1 mg/ml
Gene ID (Human) 9135
Human Swiss-Prot No. Q15276
Cellular Localization Cytoplasm; Early endosome; Recycling endosome; Cytoplasmic vesicle
Species Reactivity Human; Mouse; Rat

Background

Rab effector protein acting as a linker between gamma-adaptin, RAB4A, and RAB5A. Involved in endocytic membrane fusion and membrane trafficking of recycling endosomes. Stimulates RABGEF1-mediated nucleotide exchange on RAB5A. Proteolytic cleavage by caspases in apoptotic cells causes loss of endosome fusion activity. Belongs to the rabaptin family. Forms a heterodimer with RABGEF1; the heterodimer binds RAB4A and RAB5A activated by GTP-binding. Also binds TSC2, GGA1, GGA2, GGA3, AP1G1, and AP1G2.

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