ELK Biotechnology ATPBD3 rabbit pAb
ATPBD3 rabbit pAb는 인간, 랫, 마우스 시료에서 ATPBD3 단백질 검출용 폴리클로날 항체입니다. WB와 ELISA에 적합하며, 고순도 IgG 형식으로 제공됩니다. 인간 ATPBD3 유래 펩타이드로 면역화되어 높은 특이성과 재현성을 보장합니다.
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제품명
ATPBD3 rabbit pAb
공급업체
ELK Biotechnology
제품 설명
ATPBD3 rabbit pAb는 인간 ATPBD3 단백질을 인식하는 폴리클로날 항체로, WB 및 ELISA 실험에 활용됩니다. 본 항체는 인간 ATPBD3의 합성 펩타이드(AA 291–340)로 면역화되어 제작되었으며, 세포질 내 단백질 검출에 적합합니다.
제품 스펙
| 항목 | 내용 |
|---|---|
| Product name | ATPBD3 rabbit pAb |
| Alternative Names | CTU1; ATPBD3; NCS6; Cytoplasmic tRNA 2-thiolation protein 1; ATP-binding domain-containing protein 3; Cancer-associated gene protein; Cytoplasmic tRNA adenylyltransferase 1 |
| Applications | WB; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000 ELISA: 1/20000 Not yet tested in other applications |
| Immunogen | Synthesized peptide derived from human ATPBD3 (AA range: 291–340) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 36 kD |
| GeneID (Human) | 90353 |
| Human Swiss-Prot No | Q7Z7A3 |
| Cellular Localization | Cytoplasm |
| Species Reactivity | Human; Rat; Mouse |
Background
Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu), and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position.
Pathway: tRNA modification; 5-methoxycarbonylmethyl-2-thiouridine-tRNA biosynthesis.
Similarity: Belongs to the ttcA family, CTU1/NCS6/ATPBD3 subfamily.
Subunit: Component of a complex at least composed of URM1, CTU2/NCS2, and ATPBD3/NCS6. May form a heterodimer with CTU2/NCS2.
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