ELK Biotechnology β-1,4-Gal-T2 rabbit pAb
β-1,4-Gal-T2 단백질을 인식하는 토끼 폴리클로날 항체로, IHC, IF, ELISA에 적합합니다. 인간 및 마우스 시료에 반응하며, 골지체 막 단백질 검출에 활용됩니다. -20°C에서 1년 보관 가능합니다.
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제품명
β-1,4-Gal-T2 rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | B4GALT2; Beta-1; 4-galactosyltransferase 2; Beta-1,4-GalTase 2; Beta4Gal-T2; b4Gal-T2; UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 2; UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 2 |
| Applications | IHC; IF; ELISA |
| Recommended Dilutions | Immunohistochemistry: 1/100 - 1/300 ELISA: 1/20000 Not yet tested in other applications |
| Immunogen | Synthesized peptide derived from the C-terminal region of human β-1,4-Gal-T2 |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Gene ID (Human) | 8704 |
| Human Swiss-Prot No. | O60909 |
| Cellular Localization | Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein; Trans cisternae of Golgi stack |
| Species Reactivity | Human; Mouse |
Background
This gene is one of seven beta-1,4-galactosyltransferase (beta4GalT) genes. They encode type II membrane-bound glycoproteins that have exclusive specificity for the donor substrate UDP-galactose, transferring galactose in a beta1,4 linkage to acceptor sugars such as GlcNAc, Glc, and Xyl. Each beta4GalT plays a distinct role in the biosynthesis of glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus, remaining uncleaved to function as a transmembrane anchor. By sequence similarity, beta4GalTs form four groups: beta4GalT1/2, beta4GalT3/4, beta4GalT5/6, and beta4GalT7. The enzyme encoded by this gene synthesizes N-acetyllactosamine in glycolipids and glycoproteins.
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