ELK Biotechnology Catalase (phospho Tyr386) rabbit pAb
Catalase 단백질의 Tyr386 인산화 부위를 인식하는 토끼 다클론 항체로, WB, IHC, IF, ELISA에 사용 가능. 산화 스트레스 연구 및 관련 질환 연구에 적합. 인간, 마우스, 랫트 반응성.
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Catalase (phospho Tyr386) rabbit pAb
제품 개요
Catalase 단백질의 Tyr386 인산화 부위를 인식하는 토끼 다클론 항체입니다. 산화 스트레스 방어 기전에 중요한 역할을 하는 Catalase 단백질 연구에 활용됩니다.
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | Catalase (phospho Tyr386) rabbit pAb |
| Alternative Names | CAT; Catalase |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000 Immunohistochemistry: 1/100 - 1/300 ELISA: 1/20000 Not yet tested in other applications |
| Immunogen | The antiserum was produced against synthesized peptide derived from human Catalase around the phosphorylation site of Tyr385 (AA range: 361–410) |
| Host | Rabbit |
| Storage | -20°C, 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 59 kDa |
| Gene ID (Human) | 847 |
| Human Swiss-Prot No. | P04040 |
| Cellular Localization | Peroxisome |
| Species Reactivity | Human; Mouse; Rat |
Background
This gene encodes catalase, a key antioxidant enzyme in the body’s defense against oxidative stress. Catalase is a heme enzyme located in the peroxisome of nearly all aerobic cells. It converts hydrogen peroxide into water and oxygen, thereby mitigating its toxic effects. Oxidative stress is implicated in the development of chronic diseases such as diabetes, asthma, Alzheimer’s disease, systemic lupus erythematosus, rheumatoid arthritis, and cancers. Polymorphisms in this gene can reduce catalase activity, though acatalasemia is the only disease directly caused by mutations in this gene (RefSeq, Oct 2009).
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