Thermo Fisher Scientific AKIP1 Monoclonal Antibody (OTI1E3), TrueMAB
AKIP1 단백질을 인식하는 Mouse monoclonal antibody로, Western blot에 최적화됨. Human 시료에 반응하며, Lyophilized 형태로 제공. PBS buffer(8% trehalose) 내 보존, -20°C에서 저장. 연구용으로 NF-κB 신호전달 연구에 활용 가능.
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Applications
- Western Blot (WB): Tested dilution 1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1E3 |
| Immunogen | Full length human recombinant protein of human AKIP1 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
AKIP1 enhances NF-κB transcriptional activity by regulating the nuclear localization of the NF-κB subunit RELA and promoting the phosphorylation of RELA by PRKACA. It modulates the effect of the cAMP-dependent protein kinase signaling pathway on the NF-κB activation cascade.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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