Thermo Fisher Scientific HMGB2 Polyclonal Antibody
HMGB2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, ICC/IF에 사용 가능하며 인간에 반응. 고순도 항원 친화 크로마토그래피 정제, 액상 형태로 제공. 연구용으로만 사용.
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Thermo Fisher Scientific HMGB2 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human HMGB2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2792715 |
Product Specific Information
- Keep as concentrated solution.
- Predicted reactivity: Mouse (100%), Bovine (100%).
- Positive Control: 293T, A431, HeLa, HepG2, HMGB2-transfected 293T.
- Centrifuge briefly prior to opening the vial.
Target Information
HMGB2 encodes a member of the non-histone chromosomal high mobility group protein family. These chromatin-associated proteins are widely distributed in the nucleus of higher eukaryotic cells. In vitro studies show that HMGB2 can bend DNA and form DNA circles, suggesting a role in promoting DNA flexibility and facilitating cooperative interactions between cis-acting proteins. It is also implicated in DNA end-joining during double-strand break repair and V(D)J recombination.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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