Thermo Fisher Scientific SQRDL Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1.0 µg/mL

-

Product Specifications

Species Reactivity

Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Immunogen sequence: AQSGILDRTM CLIMKNQRPI KKYDGYTSCP LVTGYNRVIL AEFDYTAQPL (aa 351-400). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:SQRDL,uniProtId:Q9R112-1,ncbiNodeId:10090,antigenRange:351-400,antigenLength:450,antigenImageFileName:PA5-114199_SQRDL_Q9R112-1_Rabbit.svg,antigenImageFileNamePDP:PA5-114199_SQRDL_Q9R112-1_Rabbit_PDP.jpeg,sortOrder:2}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS with 2% sucrose

Contains

0.09% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2884713

Product Specific Information

Immunogen sequence: AQSGILDRTM CLIMKNQRPI KKYDGYTSCP LVTGYNRVIL AEFDYTAQPL

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Predicted homology: Cow: 93%; Dog: 86%; Guinea Pig: 86%; Horse: 93%; Human: 100%; Mouse: 86%; Pig: 100%; Rabbit: 93%; Rat: 100%; Zebrafish: 79%

Target Information

SQRDL (Sulfide: quinone oxidoreductase, mitochondrial) catalyzes the oxidation of hydrogen sulfide, with the help of a quinone. Although the SQRDL precursor protein displays a molecular weight of 50 kDa, a prominent band at about 46 kDa is detected by western blot. This discrepancy reflects the cleavage of an N-terminal targeting sequence of 4 kDa during the import of the protein into the mitochondria. SQRDL is one of the enzymes involved in H2S signaling in a discrete population of neurons, oligodendrocytes, and endothelial cells.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.