Thermo Fisher Scientific RAD51C Polyclonal Antibody
Thermo Fisher Scientific의 RAD51C Polyclonal Antibody는 인간 RAD51C 단백질을 인식하는 토끼 다클론 항체입니다. 면역세포화학(ICC/IF)에 최적화되어 있으며, 항원 친화 크로마토그래피로 정제되었습니다. PBS/glycerol 완충액에 보관되며 연구용으로만 사용 가능합니다.
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human RAD51C (Recombinant protein control fragment: Product # RP-106082) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.6 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term, store at -20°C (avoid freeze/thaw cycles). |
| Shipping conditions | Wet ice |
| RRID | AB_2662116 |
Product Specific Information
Immunogen sequence:
MRGKTFRFEMQ RDLVSFPLSP AVRVKLVSAG FQTAEELLEV KPSELSKEVG ISKAEALETL QIIRRECLTN KPRYAGTSES HKKCTALELL EQEHTQGFII TFCSALDDIL GGGVPLMKTT EICGAPGVG
- Highest antigen sequence identity to orthologs: mouse 79%, rat 82%.
Target Information
ZFPM1 is a transcription regulator involved in erythroid and megakaryocytic cell differentiation. It acts as an essential cofactor forming heterodimers with GATA family transcription factors (GATA1, GATA2, GATA3). These complexes can either activate or repress transcription depending on the cellular context.
The heterodimer is essential for activating genes such as NFE2, ITGA2B, and globin genes, while repressing KLF1 expression. ZFPM1 may also regulate genes in gonads and contribute to cardiac development alongside ZFPM2/FOG2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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