Thermo Fisher Scientific DAB1 Polyclonal Antibody
DAB1 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, 마우스 시료에서 Western blot 및 Immunoprecipitation에 적합합니다. Goat IgG 기반이며 Protein G로 정제된 액상 형태입니다. 4°C 단기 보관, -20°C 장기 보관 권장.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1 µg/mL |
| Immunoprecipitation (IP) | 5 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recognizes Dab1 of 48 kDa, corresponding to amino acids 399–555 of mouse Dab1 GST fusion protein. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.08% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2277060 |
Product Specific Information
- Suggested positive control for Western blot: 293 cells transfected with Dab1 HA tag.
- Suggested positive control for immunoprecipitation: Dab1 knockout brain p14 lysate and Dab1 wild type brain p14 lysate.
- PA1-21178 detects a band of approximately 80 kDa.
Target Information
The laminar organization of multiple neuronal types in the cerebral cortex is required for normal cognitive function. In mice, the disabled-1 (Dab1) gene plays a central role in brain development, directing the migration of cortical neurons past previously formed neurons to reach their proper layer. This gene is similar to disabled-1, and the protein encoded by this gene is thought to be a signal transducer that interacts with protein kinase pathways to regulate neuronal positioning in the developing brain. Alternatively spliced transcript variants of this gene have been reported, but their full-length nature has not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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