ELK Biotechnology SCN1A rabbit pAb

SCN1A rabbit pAb

제품 개요

SCN1A 단백질을 인식하는 토끼 폴리클로날 항체로, 전압 의존성 나트륨 채널 연구에 활용됩니다. 다양한 응용 분야(WB, IHC, IF, ELISA)에 적합하며, 사람, 마우스, 랫트 시료에서 반응성을 보입니다.

제품 정보

Background

Voltage-dependent sodium channels are heteromeric complexes that regulate sodium exchange between intracellular and extracellular spaces and are essential for the generation and propagation of action potentials in muscle cells and neurons. Each sodium channel is composed of a large pore-forming, glycosylated alpha subunit and two smaller beta subunits.
This gene encodes a sodium channel alpha subunit, which has four homologous domains, each containing six transmembrane regions. Allelic variants of this gene are associated with generalized epilepsy with febrile seizures and epileptic encephalopathy. Alternative splicing results in multiple transcript variants. The RefSeq Project has decided to create four representative RefSeq records. Three of the transcript variants are supported by experimental evidence, and the fourth contains alternate 5′ untranslated exons.