ELK Biotechnology SYCM rabbit pAb
Human SYCM 단백질에 대한 rabbit polyclonal antibody로, WB에 적합하며 1:500~1:2000 희석 권장. 미토콘드리아 매트릭스에서 발현되는 단백질을 인식. 단백질 합성 관련 연구 및 신경질환 연관성 분석에 활용 가능.
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제품명
SYCM rabbit pAb
제품 개요
Human SYCM 단백질을 인식하는 rabbit polyclonal antibody로, 단백질 합성 및 미토콘드리아 기능 연구에 사용됩니다.
제품 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | Probable cysteine--tRNA ligase, mitochondrial (EC 6.1.1.16); Cysteinyl-tRNA synthetase; CysRS |
| Applications | WB |
| Recommended Dilutions | WB 1:500–2000 |
| Immunogen | Synthesized peptide derived from human SYCM (AA range: 95–145) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 60 kD |
| GeneID (Human) | 79587 |
| Human Swiss-Prot No | Q9HA77 |
| Cellular Localization | Mitochondrion matrix |
| Species Reactivity | Human; Mouse |
Background
This gene encodes a putative member of the class I family of aminoacyl-tRNA synthetases. These enzymes play a critical role in protein biosynthesis by charging tRNAs with their cognate amino acids. The protein is encoded by the nuclear genome but imported into the mitochondrion, where it catalyzes the ligation of cysteine to tRNA molecules. A splice-site mutation in this gene has been associated with a novel progressive myoclonic epilepsy disease showing symptoms similar to MERRF syndrome. (RefSeq, Mar 2015)
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