ELK Biotechnology SEC61B Polyclona Antibody
SEC61B 단백질에 특이적인 폴리클로날 항체로, IHC 및 ELISA에 적합합니다. 인간, 마우스, 랫트에 반응하며, 인간 SEC61B 유래 합성 펩타이드로 면역화되었습니다. 내막 단백질 연구 및 단백질 수송 메커니즘 분석에 유용합니다.
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제품명
SEC61B Polyclonal Antibody
제품 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | Protein transport protein Sec61 subunit beta |
| Applications | IHC; ELISA |
| Recommended Dilutions | IHC-p: 1:50–200, ELISA (peptide): 1:5000–20000 |
| Immunogen | Synthesized peptide derived from human SEC61B (AA range: 30–110) |
| Host | Rabbit |
| Storage | -20 °C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| GeneID (Human) | 10952 |
| Human Swiss-Prot No | P60468 |
| Species Reactivity | Human; Mouse; Rat |
| Cellular Localization | Endoplasmic reticulum membrane; Single-pass membrane protein |
Background
The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. Oligomers of the Sec61 complex form a transmembrane channel through which proteins are translocated across and integrated into the ER membrane. This complex consists of three membrane proteins — alpha, beta, and gamma — and this gene encodes the beta-subunit. The Sec61 subunits are also observed in the post-ER compartment, suggesting that these proteins can escape the ER and recycle back. There is evidence for multiple polyadenylated sites for this transcript.
[provided by RefSeq, Jul 2008]
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