ELK Biotechnology SEK1/MKK4 (phospho-Ser80) rabbit pAb
SEK1/MKK4 (phospho-Ser80) rabbit polyclonal antibody로 MAPK 신호전달 관련 단백질 분석에 적합. WB 및 IHC에 사용 가능하며, 인산화된 Ser80 부위 특이적 인식. 사람, 마우스, 랫트 시료에 반응. 고순도 IgG 형태로 안정적 저장 가능.
- 카탈로그번호
- ES13165-xxxxx (2개 옵션)
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다ELK Biotechnology · ELK Biotechnology SEK1/MKK4 (phospho-Ser80) rabbit pAb
제품명
SEK1/MKK4 (phospho-Ser80) rabbit pAb
공급업체
ELK Biotechnology
제품 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | Dual specificity mitogen-activated protein kinase kinase 4 (MAP kinase kinase 4) (MAPKK 4) (EC 2.7.12.2) (JNK-activating kinase 1) (MAPK/ERK kinase 4) (MEK 4) (SAPK/ERK kinase 1) (SEK1) (Stress-activated protein kinase kinase 1) (SAPK kinase 1) (SAPKK-1) (SAPKK1) (c-Jun N-terminal kinase kinase 1) (JNKK) |
| Applications | WB; IHC |
| Recommended Dilutions | WB: 1:500–2000; IHC-p: 1:50–300 |
| Immunogen | Synthesized phospho peptide around human SEK1 (Ser80) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 44 kD |
| Gene ID (Human) | 6416 |
| Human Swiss-Prot No. | P45985 |
| Cellular Localization | Cytoplasm, Nucleus |
| Species Reactivity | Human; Mouse; Rat |
배경 (Background)
This gene encodes a member of the mitogen-activated protein kinase (MAPK) family. Members of this family act as an integration point for multiple biochemical signals and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation, and development. They form a three-tiered signaling module composed of MAPKKKs, MAPKKs, and MAPKs. This protein is phosphorylated at serine and threonine residues by MAPKKKs and subsequently phosphorylates downstream MAPK targets at threonine and tyrosine residues. A similar protein in mouse has been reported to play a role in liver organogenesis. A pseudogene of this gene is located on the long arm of chromosome X. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
ELK Biotechnology 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.