ELK Biotechnology SG196 rabbit pAb

제품 설명

ELK Biotechnology SG196 rabbit pAb는 인간 SG196 단백질을 인식하는 폴리클로날 항체로, Western Blot(WB) 및 Immunohistochemistry(IHC)에 적합합니다. 본 항체는 합성 펩타이드를 면역원으로 사용하여 제작되었습니다.

제품 특성

Background

This gene encodes a protein that may be involved in the presentation of the laminin-binding O-linked carbohydrate chain of alpha-dystroglycan (a-DG), which forms transmembrane linkages between the extracellular matrix and the exoskeleton. Some pathogens use this O-linked carbohydrate unit for host entry. Loss of function compound heterozygous mutations in this gene were found in a human patient affected by the Walker-Warburg syndrome (WWS) phenotype. Mice lacking this gene contain misplaced neurons (heterotopia) in some regions of the brain, possibly from defects in neuronal migration. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, May 2013]