ELK Biotechnology SH3G1 rabbit pAb
SH3G1 단백질을 인식하는 rabbit polyclonal antibody로, WB 실험에 적합합니다. 인간, 생쥐, 랫트 반응성이 있으며, 세포 내막 및 신경세포의 시냅스 후 엔도솜에 위치합니다. -20°C에서 1년 보관 가능하며 농도는 1 mg/ml입니다.
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제품명
SH3G1 rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Applications | WB |
| Recommended Dilutions | WB 1:500–2000 |
| Immunogen | Synthesized peptide derived from human SH3G1 (AA range: 112–162) |
| Species Reactivity | Human; Mouse; Rat |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| GeneID (Human) | 6455 |
| Human Swiss-Prot No | Q99961 |
| Cellular Localization | Cytoplasm; Early endosome membrane; Peripheral membrane protein; Cell projection, podosome; Associated with postsynaptic endosomes in hippocampal neurons |
| Storage | -20°C / 1 year |
Background
This gene encodes a member of the endophilin family of Src homology 3 domain-containing proteins. The encoded protein is involved in endocytosis and may also play a role in the cell cycle. Overexpression of this gene may contribute to leukemogenesis, and the encoded protein has been implicated in acute myeloid leukemia as a fusion partner of the myeloid-lymphoid leukemia protein. Pseudogenes are located on the long arm of chromosomes 11 and 17. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]
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