Thermo Fisher Scientific SLITRK3 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:2,500-1:5,000

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human SLITRK3. Recombinant protein control fragment (Product #RP-108201). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:SLITRK3,uniProtId:O94933-1,ncbiNodeId:9606,antigenRange:762-904,antigenLength:977,antigenImageFileName:PA5-83892_SLITRK3_O94933-1_Rabbit.svg,antigenImageFileNamePDP:PA5-83892_SLITRK3_O94933-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.2 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2791044

Product Specific Information

Immunogen sequence: EEVAVSSAQE AGSAERGGPG TQPPGMGEAL LGSEQFAETP KENHSNYRTL LEKEKEWALA VSSSQLNTIV TVNHHHPHHP AVGGVSGVVG GTGGDLAGFR HHEKNGGVVL FPPGGGCGSG SMLLDRERPQ PAPCTVGFVD CLY

Target Information

SLIT and NTRK-like family 3 (Slitrk3) is a member a protein family consisting of six homologous transmembrane proteins (Slitrk1-6) that share two conserved leucine-rich repeat domains in the extracellular domain and have significant homology to Slit, a secreted axonal growth-controlling protein. These proteins are also homologous to trk neurotrophin receptors in their intracellular domains. Expression of Slitrk proteins is highly restricted to neural and brain tumor tissues, but varies within the protein family. Like every other Slitrk protein except Slitrk1, overexpression of Slitrk3 inhibited neurite outgrowth in cultured neurons, suggesting that these proteins are involved in the control of neurite outgrowth.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.