Thermo Fisher Scientific CRYAB Monoclonal Antibody (OTI6D11), TrueMAB
CRYAB 단백질을 인식하는 마우스 모노클론 항체로, WB, IHC, ICC/IF, Flow, IP 등 다양한 응용에 적합함. 고순도 친화 크로마토그래피 정제, PBS/BSA/glycerol 버퍼에 저장. 인간 및 랫트 반응성, 연구용으로만 사용.
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카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific CRYAB Monoclonal Antibody (OTI6D11), TrueMAB
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50 |
| Immunocytochemistry (ICC/IF) | 1:50–1:100 |
| Flow Cytometry (Flow) | 1:100 |
| Immunoprecipitation (IP) | 2 µg/500 µL |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI6D11 |
| Immunogen | Full-length human recombinant CRYAB protein produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Lens proteins consist almost entirely of crystallins (about 95%). Crystallins are also found in vertebrate skeletal muscle tissue. In the lens, their structural function is to maintain the proper refractive index. The mammalian lens contains three major classes of crystallins: alpha, beta, and gamma.
Alpha-crystallin is the largest and composed of two primary gene products, alpha-A and alpha-B. Alpha-crystallin comprises 40% of total lens protein and also acts as a chaperone to prevent protein aggregation that may lead to cataract formation.
Phosphorylated states of alpha-crystallin occur in response to cellular stress and may serve structural and maintenance roles. Alpha-B crystallin has been linked to Alexander’s disease, where it accumulates in brain cells of affected individuals.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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