Thermo Fisher Scientific Parkin Polyclonal Antibody
Parkin 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC, ICC, Flow Cytometry 등 다양한 응용에 적합. 인간 및 생쥐 반응성. KLH 결합 합성 펩타이드로 면역화. 고순도 Protein A 정제, 액상 형태로 제공.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000 | View 4 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:100 | – |
| Immunocytochemistry (ICC/IF) | 1:10–1:50 | View 2 publications |
| Flow Cytometry (Flow) | 1:10–1:50 | – |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Published Species | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide between 387–417 amino acids from the C-terminal region of human Parkin |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography, Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at −20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2159914 |
Target Information
The precise function of the Parkin gene is unknown; however, the encoded protein is a component of a multiprotein E3 ubiquitin ligase complex that mediates the targeting of substrate proteins for proteasomal degradation. Mutations in this gene are known to cause Parkinson disease and autosomal recessive juvenile Parkinson disease. Alternative splicing produces multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but currently lack transcript support.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(PA5-13399_Parkin_O60260-1_Rabbit.svg 및 PA5-13399_Parkin_O60260-1_Rabbit_PDP.jpeg)
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