Thermo Fisher Scientific SQRDL Polyclonal Antibody
Human SQRDL 단백질에 특이적인 Rabbit Polyclonal Antibody로, IHC(P) 등 다양한 응용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol buffer에 보관. 연구용으로만 사용 가능.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:20–1:50
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human SQRDL. Recombinant protein control fragment (Product #RP-89841) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2647906 |
Product Specific Information
Immunogen sequence:
LIIALGIQLD YEKIKGLPEG FAHPKIGSNY SVKTVEKTWK ALQDFKEGNA IFTFPNTPVK CAGAPQKIMY LSEAYFRKTG KRSKANIIFN TSLGAIFGVK KYADALQEII QERNLTVNYK KNLIEVRADK QEAVFENLD
Highest antigen sequence identity to the following orthologs:
- Mouse: 91%
- Rat: 94%
Target Information
SQRDL (Sulfide: quinone oxidoreductase, mitochondrial) catalyzes the oxidation of hydrogen sulfide with the help of a quinone.
Although the SQRDL precursor protein displays a molecular weight of 50 kDa, a prominent band at about 46 kDa is detected by western blot. This discrepancy reflects the cleavage of an N-terminal targeting sequence of 4 kDa during mitochondrial import.
SQRDL is one of the enzymes involved in H₂S signaling in neurons, oligodendrocytes, and endothelial cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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