Thermo Fisher Scientific VCPKMT Polyclonal Antibody
Human VCPKMT 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC(P)에서 1:50~1:200 희석 비율로 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS(glycerol 포함) 용액 형태로 제공. 연구용으로만 사용.
- 판매단위
- pk
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human VCPKMT. Recombinant protein control fragment (Product #RP-88861) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2649413 |
Product Specific Information
Immunogen sequence:
DTLESSLEDP LRSFVRVLEK RDGTVLRLQQ YSSGGVGCVV WDAAIVLSKY LETPEFSGDG AHALSRRSVL ELGSGTGAVG LMAATLGADV VVTDLEELQD LLKMNINMNK HLVTGSVQAK GGRNRRLSFS TRLHTDGRLH I
- Highest antigen sequence identity to orthologs:
- Mouse: 77%
- Rat: 29%
Target Information
C14orf138, also named as VCPKMT or METTL21D, is a 229 amino acid protein belonging to the methyltransferase superfamily. It localizes in the cytoplasm and interacts with ALKBH6. C14orf138 acts as a protein-lysine N-methyltransferase that specifically trimethylates Lys-315 of VCP/p97, potentially decreasing VCP ATPase activity. It exists as five isoforms. The calculated molecular weight is 26 kDa, but a 46–50 kDa protein is typically detected by western blot.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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