Thermo Fisher Scientific SARS Coronavirus Nucleoprotein Monoclonal Antibody (1C7C7)

Applications

Tested Dilution

Publications

Western Blot (WB)

1-5 µg/mL

-

Immunocytochemistry (ICC/IF)

1-5 µg/mL

-

ELISA (ELISA)

0.1-2.0 µg/mL

-

Product Specifications

Host/Isotype

Mouse / IgG2a

Class

Monoclonal

Type

Antibody

Clone

1C7C7

Immunogen

Recombinant SARS (severe acute respiratory syndrome) nucleoprotein

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Storage conditions

-20°C

Shipping conditions

Wet ice

RRID

AB_2533325

Target Information

It has recently been shown that SARS is caused by a human coronavirus. Human coronaviruses are the major cause of upper respiratory tract illness in humans, such as the common cold. Coronaviruses are positive-stranded RNA viruses, featuring the largest viral RNA genomes known to date (27-31 kb). The first step in coronavirus infection is binding of the viral spike protein, a 139-kDa protein, to certain receptors on host cells. The spike protein is the main surface antigen of the coronavirus. The most prominent protein in the culture supernatants infected with SARS virus is a 46 kDa nucleocapsid protein. This suggests that the nucleocapsid protein is a major immunogen that may be useful for early diagnostics.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.